Sylestro is a respawnable mini-boss encountered in Borderlands 3. He is a badass-class Radiation Heavy found in a remote part of Tazendeer Ruins on Nekrotafeyo.


Sylestro and his partner Atomic need to be defeated for Zer0's Target of Opportunity challenge.



Main article: Target of Opportunity (Tazendeer Ruins)


  • Unlike generic Badass Heavies, Sylestro has a large spiked fist on each hand.
  • Sylestro has an increased chance to drop the legendary Red Suit shield.
  • On Mayhem Mode 4, Sylestro has a chance to drop the legendary Amara class mod Spiritual Driver.

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