While he performs the basic spider melee attack that deals corrosive damage, he can also spawn Black Widow Spiders from his abdomen. He is vulnerable to incendiary damage while being resistant to corrosive damage. His very large abdomen is a critical hit point.
- The origin of Spiderpants came from the Gearbox forums, where a subsequently banned user posted a guide on how to kill spiderants, but misspelled spiderants as "spiderpants". This typo was immediately adopted by the community, eventually leading to the formation of The Cult of the the Spiderpants. Gearbox responded by adding spiderpants as a rare spawn within Tiny Tina's Assault on Dragon Keep.
- The monocle and tophat worn by Spiderpants is a reference to the monocle and tophat featured in every profile photo of forum moderator Psychichazard.