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Poisonous Spiderants are larger version of the Spiderant Worker and are distinguished by their intense green coloration.
Poisonous Spiderants are primarilly ranged attackers, but will slash with their forelimbs if targets get within melee range. They launch webs and globs which deal corrosive damage on impact. Simillar to some other spiderants, they occassionaly stop in their tracks, rise their heads up in the air, and let out a distinctive sound. After stomping ground with their forelimbs, a single large glob is released. After a short pause, this glob explodes creating a large cloud which engulfs all nearby enemies and deals moderate corrosive damage. Poisonous Spiderants are immune to corrosive damage.
- In True Vault Hunter Mode, they are renamed Leperous Spiderant. In Ultimate Vault Hunter Mode, they are renamed Diseased Spiderant.
- Main article: Spiderant#General_Strategy