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Medical Mystery: X-Com-municate is an optional mission in Borderlands 2, available immediately upon the completion of Medical Mystery. The Vault Hunter has to kill bandits using the E-tech gun provided at the beginning of the mission.



"Now that you've found an E-tech gun, it's time to try it out!"

  • Kill bandits with E-tech gun: 0/25


Once the BlASSter is acquired, and Dr. Zed gives his spiel, a number of psychos will spawn and attack. The objective is to kill 25, and the first waves will provide 14 bandits to further that goal. Their health can be whittled down with damage from any source, but only kills made with the E-tech gun will help to fill the quota.


"Well done, brainy. Because of your research, Dr. Zed know that E-tech weapons, while visually distinctive and scientifically advanced, are still really good at killing stuff."

Turn In: Dr. Zed


  • Enemies which count towards the kill count for this mission include bandits, nomads, sand pirates, and any midget or badass versions thereof.
  • The mission Assassinate the Assassins is nearby and provides an ample source of additional bandits to kill with the mission weapon.
  • Bandits killed as part of the Rock, Paper, Genocide missions given by Marcus Kincaid count towards the kill count. This provides a quick and very easy source of kills.
  • The Bandit BlASSter looted from Doc Mercy is a weapon that's exclusive to this mission, it has several aspects that differentiate it from normal BlASSters:
    • It has a chance to be non-elemental, breaking the rules of E-tech weaponry. This is especially likely in Normal mode, but can occur in True Vault Hunter Mode and Ultimate Vault Hunter Mode as well.
    • It uses a blue rarity skin, while normal BlASSters always use a purple rarity skin.
    • It can spawn without an accessory (e.g. increased stability, etc.) or a scope, both of which are not normally allowed for E-tech weapons. This is likely due to the fact that the gun is treated like a blue rarity weapon instead of a proper E-tech one.
  • Kills made with other weapons may randomly be counted towards the kill count for this mission. Any weapons that deal splash damage will be added towards the mission objective.
    • Explosive weapons count toward killing bandits as if it was the mission assigned blaster rifle.
  • It is highly recommended that when playing as Maya, her skill tree be reworked to prevent elemental damage from killing enemies. Her Cloud Kill skill can make it extremely difficult for kills to be made with the Blasster. Short of paying to reset all skill points, the best way to accomplish the mission is to be as close to the enemy as possible too ensure that the last bullet fired gets to them as quickly as possible, though this does not guarantee that corrosive damage will not kill them first. In this case, it is best to confront enemies in groups of no more than five.
  • It is not necessary to complete this mission in order to farm Doc Mercy.


  • The mission's name is a reference to the X-COM series of games.

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