For me it has to be the Drifters. They re-spawn at an incredible rate and are pretty hard to kill without a vehicle. And even if you're in a Monster it can be hard because all of a sudden 3 might climb up out of the ground and they'll acid-blast you before you can high tail it outta there. They spill a decent amount of loot, but their presence can be very frustrating when they slow you down on your progress from point A to point B.
scythids. i hate scythids. they are small and annoying, and fly around at random making them hard to see / shoot / run over. and there is no achievement (pc) for killing them. i simply hate those damn little zergling wannabes! 
the frumious fry 05:05, July 10, 2010 (UTC)
Spiderants. Hate the one actual spot is annoying as hell to hit. Drifters, i kind of like, OP. With a double anarchy, it's a matter of watching your ammoIbanezRokr 06:19, July 10, 2010 (UTC)
ya the tiebaggers(drifter) are kind of fun it almost becomes a compatition to see who can kill the most, ok on topic now the ravager mainly when you see some health you need run for just to get blown up and have to health there beside you Aren01 06:43, July 10, 2010 (UTC)
No contest Crawmaggots are more than annoying. I hate those little bastards.Willp602 06:47, July 10, 2010 (UTC)
Maybe I was playing the game wrong, but I always thought Drifters were much easier to kill on foot than in a vehical. I agree with scythids - flying, leaping, screeching - are the most annoying. SkinBasket 12:59, July 10, 2010 (UTC)
The five year old players with stock guns and rose omegas that don't stop challenging you to a duel and then accuse YOU of being unfair when you use a vengeance or trespass to kill them. ShadyCake 15:54, July 10, 2010 (UTC)
Crawmaggots! MoFo's have insta-rammed me off the cliff sooooo many times! In Vanilla BF, it's the "zig-zag" bandit. Ya know, that lowly bandit that always moving left-right as he comes at you and dodges as you pull the trigger. Dammit, stop that! Honorable mention - baby scythids, the little pink ones that squeak. The gurls around here don't like them to be killed - "they're so cute". grrrrrr -- MeMadeIt 16:10, July 10, 2010 (UTC)
I agree with all of these, and i assume that most people will as well, however the ultimate, most annoying enemy has to be those green craw worms, they have more health than armoured ones, they jump at you like the maggot ones, and they kill you instantly.
They are supposed to have high damage, and resistance to shock and corrosive, but a hellfire or draco takes as long to kill it as a serpens or other fully-auto elemental weapon. I actually have a harder time killing them than crawmerax himself (legit gear) Zuphix 16:13, July 10, 2010 (UTC)
I have to say i strongly dislike the midgets that throw bombs. They are bastards (I can't remember there name), i went on a hunt to find a good vulcano just so i could kill them without getting to close so they could throw their WAY to powerful bombs at me. And i totally agree with MeMadelt on the crawmaggots.Humanperson 17:02, July 10, 2010 (UTC)
Ravagers. I have a love/hate relationship with them. They have killed me more than any other enemy. They're harder to kill than Badass Midgets. They have screechy (like nails on a chalkboard) voices. And, that's what makes them lovable. Aegisq3dm9 17:26, July 10, 2010 (UTC)
The Crawmaggots suck the most. Yeah, they're easy to kill but they f-up your snipes and such unexpectedly. As for drifters, just use an Anarchy and own them in seconds flat. Firefly 19 19:07, July 10, 2010 (UTC)
I hate crawmaggot that can not be stressed enough im just there chill'n and shit sniping craw when these assclowns just bust out of the ground and haul ass right at you and then suicide takeing you with them. or even worse they just relentlessly jump at you till you get downed then they skedattle off all the fricking way to the other side of the arena just to roar in unison with the other members of the craw family.(close second) the bandits that shoot at you till u down then hide from your line of sight.Mr.friend009 00:28, July 11, 2010 (UTC)
Midget ravagers and Bad-Ass midgets have to be the worst. Craw maggots are not far behind. Drifters used to give me trouble until I figured out that it's better to go out on foot with a double anarchy against them. I don't get the poster above thinking green craws are the worst. There's no way they have as much health as the other craw minions, especially the armored ones. You can waste them in 5 seconds flat with a Hellfire, and even one shot them with a Volcano and a well placed crit.
I'm surprised that nobody mentioned those stupid lance probes. They are near impossible to hit and do WAY to much damage, especially on vehicles. I do however have to give an honorable mention to craw maggots. - Uberorb (Talk)
Nobody's mentioned them cuz you're the only one having a problem with them. A Monster's rocket launcher kills them in 2 shots. A good Defiler only takes about 2 shots and a Serpens, Ogre, or Anarchy about a 2-second burst. -- MeMadeIt 03:22, July 11, 2010 (UTC)
Dr. Hax hates spineless rose omega hax users who challenge him to duels... then run away whining about him being a haxor after they feel the shield piercing wrath granted by his trustworthy Vengeance followed by a swift computer monitor to the head. He gives kudos to ShadyCake for agreeing with him. Skeve613, however, most hates every type of Crawmerax minion except the armored worms (because they are slow and die fast in the face of his beloved Serpens). 
Skeve613ask Dr. Hax 17:53, July 11, 2010 (UTC)
Uberob the lance probes are similar to sera guardians except they get closer. close enough for a shock contact grenade to punch through their overpowered shield. The most annoying enemies are suicide psychos when your dealing with about 6 enemies they suddenly get in close and explode. Even if you kill them you have to dash to cover throwing off the whole game. However while I am flaming the most annoying thing about borderlands is like everything else other people. Especially the people at about lv 30 who join lv 5's and challenge them to duels and open loot chests and grab the guns that are 25 levels below them. I say anyone sees these noobs in a game they host kick them immediatly.Mysillyideas 15:45, July 17, 2010 (UTC)
I should clear this up a little bit... sometimes when I play online, there is just enough lag that 90% of my shots will miss the lance probes. Single player is fine though. Uberorb 
I also agree with the low level players joining and taking all the good gear. when I rented BL for the PS3, thats what happened to me in 75% of the games I hosted online.
I don't like the defilers in jakobs cove because of their vomit.X-THE-MEX 00:00, July 19, 2010 (UTC)
Outriders with rocket launchers. Bouncing around like a ball and can't see a damn thing through all the smoke. Great fun. Carpathian Cookie 01:41, July 19, 2010 (UTC)
Drifters definitly even worse if there was a badass drifter, but drifters already count as badass. Sooo..... It would be doubly badass drifter
Honourable mentions to Craw maggots, ehhhh and Lance probes too cuz They iz ugly my friend! BLObOrt 17:47, July 30, 2010 (UTC)
I would have to agree about the maggots, trying to hit one of Craws spots thinking you are nowhere near a minion just to have a maggot pop up to down you in a second wind. VERY annoying!!Veggienater 21:23, July 30, 2010 (UTC)
The most annoying so far as i have not fought crabby yet, scythids, they are by far the most annoying, the ones that gave me the most trouble was the shock lance in PT 2, i did not have a good shield for most of my game so they did give me more trouble than any other enemies. xbox GT SInsterNObody
What really gets me angry are those damn psychos that haven't started running yet, but can somehow lob an axe across miles of terrain with pinpoint accuracy, doing just enough damage to upset my Hunter's aim, causing me to miss whatever I was about to send to bandit heaven. Honorable mentions to the drifters and lance probes.Moloko Symboro 10:39, August 4, 2010 (UTC)
The most annoying enemy I can actually think of are scythids. I just have a fear of freaking fast crawling black bugs that squeal and bite me. They are so freaking annoying,WHENEVER I GO TO SOME PLACE I KNOW SCYTHIDS SPAWN AROUND I GO IN A VEHICLE. Second is the drifters,they are annoying in the car but even then I ostly fled the warzone but then I heard of the orange dropsand as I was heading to see the loot......CHWARCHTK!!!!(or drifter growl,whatever) style backstabb and I develop chronic fear 109.96.217.174 16:30, October 10, 2010 (UTC)User:Kovacslorand6 MAD MELL! I hate this bastard! He kills me every time, i met him!
Kamikaze Claptraps. At least the Psychos are rather chatty. These bastards just roll up quietly and kill you. And Moloko, yeah. How the hell can they throw an axe more accurately than a bandit can shoot? 204.111.113.64 17:25, October 10, 2010 (UTC) (oops, forgot to log in. Thexare 17:26, October 10, 2010 (UTC))
My least favorite has to be Corpse Eaters, since they love to fly at you in big groups and then mob you until you get so annoyed you pull out your shotgun and blast them all to bits. Although, I have to admit it is fun hanging back with a sniper rifle and sniping them out of the sky (reminds me a lot of Duck Hunt.)