The Exterminator has a niche use due to it dealing increased damage to two specific types of enemies. It can be of use in Devil's Razor and Konrad's Hold due to the abundance of varkids and spiderants, though it is of overall questionable use due to the existence of more versatile grenade mods.
Multiple identical copies of the Exterminator can be obtained from a single piñata.
The name and flavor text are a reference to the 1997 movie Men in Black. The text is a quote by an alien impersonating a person named Edgar. The alien (referred to as "bug" in the movie) also drives a stolen pest exterminator's truck.