Medical Mystery: X-Com-municate

 is a main story mission in Borderlands 2.

Strategy
Once the gun is acquired, and Dr. Zed gives his spiel, a number of psychos will spawn and attack. The objective is to kill 25, and the first waves will provide 14 bandits to further that goal. Their health can be whittled down with damage from any source, but only kills made with the E-tech gun will help to fill the quota.

Trivia

 * The mission's name is a reference to the XCOM series of games.